其他產(chǎn)品及廠家

Quercetin；槲皮素Sophoretin；槲皮素|||Sophoretin
quercetin (sophoretin) is a natural flavonoid and is an agonist of sirt1. quercetin is also a pi3k inhibitor, inhibiting pi3kγ, pi3kδ, and pi3kβ (ic50=2.4/3.0/5.4 μm). quercetin can induce apoptosis and autophagy.
更新時(shí)間:2025-12-04
RD162；化合物RD162RD162
rd162 is a non-steroidal antiandrogen (nsaa) specifically binding to the androgen receptor (ar).
更新時(shí)間:2025-12-04
Beta-Lipotropin (1-10), porcine Acetate；化合物T21743LBeta-Lipotropin (1-10), porcine Acetate(77875-68-4
beta-lipotropin (1-10), porcine acetate (beta-lipotropin ) (beta-lph) was found to contain within its c-terminal sequence the primary structure of these peptides.
更新時(shí)間:2025-12-04
Terameprocol；化合物Terameprocoltetramethyl Nordihydroguaiaretic Acid|||EM-1421；tetramethyl Nordihydrogu
terameprocol (em-1421) is a synthetic tetra-methylated derivative of nordihydroguaiaretic acid (ndga) and transcriptional inhibitor with potential antiviral, antiangiogenic, and antineoplastic activities. terameprocol showed the strongest anti-hiv activity.
更新時(shí)間:2025-12-04
VU0483605；化合物VU0483605VU0483605
vu0483605 is an effective and selective positive allosteric modulator of mglur1 with ec50s of 390 and 356 nm for human and rat, respectively.
更新時(shí)間:2025-12-04
4-iodo-SAHA；化合物 T217494-iodo-SAHA
4-iodo-saha (1k), an orally active inhibitor of both class i and class ii histone deacetylase (hdac), exhibits ec50 values of 1.1, 0.95, 0.12, 0.24, 0.85, and 1.3 μm for skbr3, ht29, u937, ja16, and hl60 cell lines, respectively. this compound holds potential for cancer research purposes [1].
更新時(shí)間:2025-12-04
A 784168化合物 T21750A 784168
a-784168, a potent and orally active inhibitor of vanilloid receptor type 1 (trpv1), acts on a ligand-gated nonselective cation channel pivotal in integrating pain stimuli including endogenous lipids, capsaicin, heat, and low ph. it demonstrates commendable central nervous system (cns) penetration upon oral administration [1].
更新時(shí)間:2025-12-04
AL 8810；化合物 T21752AL 8810
al-8810 is an 11β-fluoro analog of pgf 2α with selective antagonist effects at the pgf 2α receptor (fp receptor) [1].
更新時(shí)間:2025-12-04
Bizine；化合物 T21756Bizine
bizine, a phenelzine analogue, is a potent and selective lsd1 inhibitor, with a b>k i of 59 nm. bizine can modulate bulk histone methylation in cancer cells. bizine has potential applications in neuroprotective [1].
更新時(shí)間:2025-12-04
Calindol (hydrochloride)；化合物 T21758Calindol (hydrochloride)
calindol (hydrochloride) is a positive allosteric modulator (pam) of calcimimetic calcium-sensing receptor (casr) with an ec50 of 132 nm.
更新時(shí)間:2025-12-04
2,3-Butanedione 2-Monoxime；化合物2,3-Butanedione 2-MonoximeDiacetyl monoxime|||2,3-Butanedione-2-monoxi
2,3-butanedione 2-monoxime (diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.
更新時(shí)間:2025-12-04
COG 133 Acetate；化合物COG 133 AcetateCOG 133 Acetate(514200-66-9 Free base)；COG 133 Acetate(514200-66-9
cog 133 acetate, (c97h181n37o19) is a peptide with the sequence ac-leu-arg-val-arg-leu-ala-ser-his-leu-arg-lys-leu-arg-lys-arg-leu-leu-amide.
更新時(shí)間:2025-12-04
LDN-211904；化合物 T21762LDN-211904
ldn-211904 oxalate (compound 32), a potent and selective ephb3 inhibitor, demonstrates an ic50 of 0.079 μm and shows good metabolic stability in mouse liver microsomes. when combined with cetuximab, it may effectively inhibit stat3-activated csc stemness and cetuximab resistance in crc [1] [2].
更新時(shí)間:2025-12-04
Lenalidomide hydrochloride；化合物 T21763Lenalidomide hydrochloride
lenalidomide hydrochloride (cc-5013 hydrochloride), a thalidomide derivative, functions as molecular glue and serves as an orally active immunomodulator. as a ligand for the ubiquitin e3 ligase cereblon (crbn), it facilitates the selective ubiquitination and degradation of the lymphoid transcription factors ikzf1 and ikzf3 through the crbn-crl4 ubiquitin ligase. specifically, lenalidomide hydrochloride inhibits the growth of mature b-cell lymphomas, including multiple myeloma, and promotes il-2
更新時(shí)間:2025-12-04
MCC-555化合物MCC-555Isaglitazone|||Netoglitazone
mcc-555 (isaglitazone) is a pparα and pparγ agonist exerting antihyperglycemic effects.
更新時(shí)間:2025-12-04
ML352；化合物 ML352ML352
ml352 is a selective and potent inhibitor of the presynaptic choline transporter (cht), inhibits non-competitive choline uptake.
更新時(shí)間:2025-12-04
MS37452；化合物MS37452MS37452
ms37452 is a competitive inhibitor of cbx7 chromodomain binding to h3k27me3 (ki = 43 ?m).
更新時(shí)間:2025-12-04
PF-562271 hydrochloride化合物PF-562271 HClPF-562271 HCl
pf-562271 hydrochloride (pf-562271 hcl) is a potent, atp-competitive, reversible inhibitor of fak with ic50 of 1.5 nm in cell-free assays, ~10-fold less potent for pyk2 than fak and >100-fold selectivity against other protein kinases, except for some cdks.
更新時(shí)間:2025-12-04
Kaempferol；山奈酚Kempferol|||Robigenin；Kempferol|||山柰酚|||山奈酚|||Robigenin
kaempferol (robigenin) is a natural flavonoid and an inverse agonist of errα and errγ. kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities.
更新時(shí)間:2025-12-04
Pyoluteorin；藤黃綠菌素Pyoluteorin
pyoluteorin is an antibiotic that inhibits oomycete fungi, including the plant pathogen pythium ultimum, and suppresses plant diseases caused by this fungus. pyoluteorin induces human triple-negative breast cancer mda-mb-231 cells apoptosis in vitro.
更新時(shí)間:2025-12-04
Reserpine hydrochloride化合物 T21772Reserpine hydrochloride|||Reserpine Hydrochloride
reserpine hydrochloride is an alkaloid found in the roots of rauwolfia serpentina and r. vomitoria. reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. it has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
更新時(shí)間:2025-12-04
SP-141；化合物SP 141SP 141；SP 141
sp 141 is a mdm2 inhibitor.sp-141 promotes mdm2 auto-ubiquitination and degradation, with anticancer activity.
更新時(shí)間:2025-12-04
Tenofovir maleate；化合物 T21775Tenofovir maleate
tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used in the treatment of hiv and chronic hepatitis b.
更新時(shí)間:2025-12-04
(+/-)-Terreic acid；(+/-)土曲霉酸(+/-)-Terreic acid
(+/-)-terreic acid is a natural product found in kulturen v. aspergillus flavipes.
更新時(shí)間:2025-12-04
VU0359595；化合物VU0359595VU0359595-1|||CID-53361951|||ML-270；VU0359595-1|||CID-53361951|||ML-270
vu0359595 (ml-270) is a potent and selective pharmacological phospholipase d1 (pld1) inhibitor with an ic50 of 3.7 nm. vu0359595 is >1700-fold selective for pld1 over pld2 (ic50 of 6.4 μm). vu0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases.
更新時(shí)間:2025-12-04
10-DEBC hydrochloride；化合物 T2177810-DEBC hydrochloride
10-debc hydrochloride, a selective akt inhibitor demonstrating an ic50 value of 1.28 μm, is identified as a novel anti-tuberculosis compound [1] [2].
更新時(shí)間:2025-12-04
AMI5；化合物AMI-5AMI 5|||Eosin Y Disodium|||AMI-5；AMI 5|||Eosin Y Disodium|||AMI-5
ami5 (eosin y disodium) is a versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with hematoxylin. it is also used in special culture media.
更新時(shí)間:2025-12-04
A-286982；化合物A 286982A-286982
a 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (lfa-1) and intercellular adhesion molecule-1.
更新時(shí)間:2025-12-04
A 77636 hydrochloride；鹽酸A77636A77636 hydrochloride；鹽酸A77636|||A77636 hydrochloride
a 77636 hydrochloride is a potent, orally active, selective and long acting dopamine d1 receptor agonist (pki=7.40; ki=39.8 nm). a 77636 hydrochloride shows antiparkinsonian activity. a 77636 hydrochloride is functionally inactive at dopamine d2 receptor.
更新時(shí)間:2025-12-04
AG-183；化合物 T21783AG-183
(z)-tyrphostin a51 is the z configuration of lanoconazole a51. tyrphostin a51 is a potent protein tyrosine kinase (ptk) inhibitor which inhibits the volume-sensitive release of [3 h]taurine in primary astrocyte cultures in a dose-dependent manner. tyrphostin a51 markedly reduces cellular tyrosyl phosphorylation level. tyrphostin a51 inhibits both basal and egf-induced human bone cell proliferation [1] [2].
更新時(shí)間:2025-12-04
AG957；化合物Tyrphostin AG957u00A0AG957
tyrphostin ag957, a tyrosine kinase inhibitor with anti-bcr/abl tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in chronic myelogenous leukemia hematopoietic progenitors[1].
更新時(shí)間:2025-12-04
Apogossypolone (ApoG2)；化合物 T21786Apogossypolone (ApoG2)
apogossypolone (apog2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting bcl-2 family proteins with k i values of 35, 25 and 660 nm for bcl-2, mcl-1 and bcl-x l, respectively. apogossypolone shows antitumor activities, induces cell apoptosis [1] and autophagy [2]. apogossypolone also has antifungal activity [3].
更新時(shí)間:2025-12-04
B-HT 933 dihydrochloride；化合物 T21787B-HT 933 dihydrochloride
azepexole dihydrochloride (b-ht 933), a potent and selective alpha 2-adrenoceptor agonist, exhibits affinity for α2a-, α2b-, and α2c-adrenoceptor subtypes with pkis of 8.3, 7.6, and 7.5, respectively [1]. it elicits a concentration-dependent inhibition of peristaltic contractions, evidenced by an ic50 of 78.72 nm.
更新時(shí)間:2025-12-04
Azepexole hydrochloride；化合物T21787L4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydr
azepexole hydrochloride (4h-oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)) is a potent α2-adrenoceptor agonist with anaesthetic effects.
更新時(shí)間:2025-12-04
BD 1008 dihydrobromide；N-[2-(3,4-二氯苯基)乙基]-N-甲基-1-吡咯烷乙胺二氫溴酸鹽BD 1008 dihydrobromide
bd 1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (ki = 2 nm). bd 1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors.
更新時(shí)間:2025-12-04
Triptolide；雷公藤甲素PG490|||NSC 163062；PG490|||NSC 163062|||雷公藤甲素
triptolide (pg490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of nf-κb activation. triptolide exhibits immunosuppressive, anti-rheumatic, anti-inflammatory, anti-proliferative and anti-tumor activities.
更新時(shí)間:2025-12-04
BMS 182874 hydrochloride；化合物BMS 182874 hydrochlorideBMS 182874 hydrochloride
bms 182874 hydrochloride is a nonpeptide endothelin (el) receptor antagonist.
更新時(shí)間:2025-12-04
CGP 3466B maleate馬來(lái)酸CGP3466B馬來(lái)酸CGP3466B|||Omigapil (Maleate)|||Omigapil maleate
cgp 3466b maleate (omigapil maleate) is an orally bioavailable gapdh nitrosylation inhibitor. omigapil maleate abrogates aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. omigapil maleate has the potential for the research of alzheimer´s disease. omigapil maleate (cgp3446b maleate) is a apoptosis inhibitor. omigapil maleate can be used for the research of congenital muscular dystrophy (cmd).
更新時(shí)間:2025-12-04
CRT5；化合物 T21795CRT5
crt5, a pyrazine benzamide, is a potent and selective pkd inhibitor. the vegf-induced phosphorylation of three pkd substrates (ic50s = 1, 2, and 1.5 nm for pkd1, pkd2, and pkd3, respectively), histone deacetylase 5, creb (camp-response-element-binding protein), and hsp27 (heat-shock protein 27) at ser82, is also inhibited by crt5. crt5 decreases vegf-induced endothelial migration, proliferation, and tubulogenesis[1].
更新時(shí)間:2025-12-04
Dynamin inhibitory peptide Acetate；化合物T21798LDynamin inhibitory peptide Acetate(251634-21-6 Free bas
dynamin inhibitory peptide acetate is a peptide with the sequence gln-val-pro-ser-arg-pro-asn-arg-ala-pro that inhibit the gtpase dynamin.
更新時(shí)間:2025-12-04
Hexythiazox；噻螨酮Hexythiazox
hexythiazox is a mite growth regulator and a thiazolidine based acaricide that has long-lasting effects against many kinds of mites and is applied at any stage of the plant growth from budding to fruiting.
更新時(shí)間:2025-12-04
Guanylyl Imidodiphosphate；化合物 T21803Guanylyl Imidodiphosphate
guanylyl imidodiphosphate trisodium (guanosine 5´-[β,γ-imido]triphosphate), a non-hydrolysable gtp analogue, activates adp-ribosylation factor (arf) and strongly stimulates adenylate cyclase. it is utilized in protein synthesis studies [1] [2] [3].
更新時(shí)間:2025-12-04
GW 610；化合物GW 610GW 610
gw 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. in mcf-7 and mda 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (gi50) < 0.1 nm) was observed.
更新時(shí)間:2025-12-04
HNHA；N-羥基-7-(2-萘硫基)-庚酰胺HNHA
hnha is an inhibitor of hdac.
更新時(shí)間:2025-12-04
INCA-6化合物INCA-6Triptycene-1,4-quinone
inca-6 (triptycene-1,4-quinone) is a cell-permeable nfat inhibitor. inca-6 inhibits of cn-nfat signaling by targeting of nfat(p) substrate to the calcineurin (cn) phosphatase site.
更新時(shí)間:2025-12-04
Inotilone；化合物InotiloneInotilone
inotilone is a major component of inonotus linteus, a traditional chinese medical herb and can be used for research of metastatic lung cancer cells.
更新時(shí)間:2025-12-04
LH 21；化合物 T21811LH 21
lh-21 is a potent in vivo neutral cannabinoid cb1 receptor antagonist. lh-21 reduces food intake and body weight gain in obese zucker rats., and results in a dose-dependent inhibition of feeding [1].
更新時(shí)間:2025-12-04
LT175；化合物 T21812LT175|||LT 175|||LT-175|||LT175；0
lt175, a dual pparα/γ ligand, demonstrates potent insulin-sensitizing effects while exhibiting reduced adipogenic properties. this compound is an orally active partial agonist targeting pparγ, with ec50 values of 0.22 μm for hpparα, 0.26 μm for mpparα, and 0.48 μm for hpparγ. lt175 specifically interacts with pparγ, influencing the recruitment of coregulators such as the cyclic-amp response element-binding protein-binding protein and nuclear corepressor 1 (ncor1). additionally, lt175´s int
更新時(shí)間:2025-12-04
OAC3；化合物OAC34-fluoro-N-(1H-indol-5-yl)benzamide；4-fluoro-N-(1H-indol-5-yl)benzamide
oac3 (4-fluoro-n-(1h-indol-5-yl)benzamide) is an activator of octamer-bound transcription factor 4.
更新時(shí)間:2025-12-04
ONO 4817；化合物 T21814ONO 4817
ono-4817 is a broad-spectrum matrix metalloproteinase (mmp) inhibitor that potentially mitigates atherosclerotic neointimal proliferation and atheromatous plaque progression by suppressing matrix metalloproteinases (mmps). it effectively reduces the development of aortic intimal hyperplasia in experimental hyperlipidemic rabbits [1].
更新時(shí)間:2025-12-04

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